In the 1911 Encyclopædia Britannica:
- Santa Cruz, Álvaro de Bazan, 1st Marquis of
- Santa Cruz (Bolivia) in Bolivia
- Santa Cruz (California), in the United States
- Santa Cruz (archipelago), an archipelago in the Pacific Ocean
- Santa Cruz (Philippine Islands), capital of La Laguna on Luzon
- Santa Cruz de Tenerife, capital of the Canary Islands