File:Lineage-Specific-Gene-Duplication-and-Loss-in-Human-and-Great-Ape-Evolution-pbio.0020207.g003.jpg
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Summary
| Description |
English: (A) Human duplication of a cluster of genes at Chromosome 5q13.3. is shown by two separate, and sometimes multiple, red BAC probe (CTD-2288G5) signals in interphase cells, with only one green BAC probe signal (RP11-1077O1) for a flanking region. Metaphase FISH shows both probes at band 5q13. The third nucleus in (A) shows four signals of the control probe (green) and eight copies of the BAC probe duplicated in the aCGH assay, consistent with the pattern expected in an S/G2 nucleus. |
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| Source | Image file from Fortna A, Kim Y, MacLaren E, Marshall K, Hahn G, Meltesen L, Brenton M, Hink R, Burgers S, Hernandez-Boussard T, Karimpour-Fard A, Glueck D, McGavran L, Berry R, Pollack J, Sikela J (2004). "Lineage-Specific Gene Duplication and Loss in Human and Great Ape Evolution". PLOS Biology. DOI:10.1371/journal.pbio.0020207. | ||
| Author | Fortna A, Kim Y, MacLaren E, Marshall K, Hahn G, Meltesen L, Brenton M, Hink R, Burgers S, Hernandez-Boussard T, Karimpour-Fard A, Glueck D, McGavran L, Berry R, Pollack J, Sikela J | ||
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  This file is licensed under the Creative Commons Attribution 3.0 Unported license.
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 20:53, 13 June 2014 | | 448 × 308 (21 KB) | VIAFbot | Automatic upload of media from: doi:10.1371/journal.pbio.0020207 |
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