File:Ranking-Candidate-Disease-Genes-from-Gene-Expression-and-Protein-Interaction-A-Katz-Centrality-pone.0024306.g001.jpg

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English: The area of the nodes is proportional to xi—the difference in expression level. The width of the edges represents the coupling strength wij in the protein interaction network. The color of the nodes represents our score and the numbers shows their order in this ranking. Panels A and B shows the result of two values of φ—a low value of φ (2% of the maximal possible) in A, and a high value of φ (98% of max). Low φ-values put an emphasis on the difference in expression level; high φ-values stress the proximity to other vertices with high score. We also assume η≫1.
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Source Image file from Zhao J, Yang T, Huang Y, Holme P (2011). "Ranking Candidate Disease Genes from Gene Expression and Protein Interaction: A Katz-Centrality Based Approach". PLOS ONE. DOI:10.1371/journal.pone.0024306. PMID 21912686. PMC: 3166320.
Author Zhao J, Yang T, Huang Y, Holme P
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current14:01, 23 July 2014Thumbnail for version as of 14:01, 23 July 2014430 × 238 (51 KB)Recitation-botAutomatic upload of media from: doi:10.1371/journal.pone.0024306

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