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SAN ANTONIO RIVER, a river of Texas, rising in Bexar co., and following a general S. E. course of nearly 200 m. to Espiritu Santo bay. It unites with the Guadalupe about 12 m. from its mouth. Its largest tributaries are the Medina and Salado in Bexar co., and the Cibolo in Karnes co. The chief towns on its banks are San Antonio and Goliad.