&c., can have sufficient time or life left in them to carry on series of experiments and series of cultures, but they can and do supply to the man in the laboratory at home grand material for him to carry the thing through; meanwhile we wait that man and do the best we can.
The net results of laboratory investigation, according to the French doctors, is that the mycetozoic malarial bacillus, the microbe of paludism, is amœboid in its movements, acting on the red corpuscles, leaving nothing of them but the dark pigment found in the skin and organs of malarial subjects.[1] The German doctors make a practice of making microscopic examinations of the blood of a patient, saying that the microbes appear at the commencement of an attack of fever, increase in quantity as the fever increases, and decrease as it decreases, and from these investigations they are able to judge fairly accurately how many remissions may be expected; in fact to judge of the severity of the case which, taken with the knowledge that quinine only affects malarial microbes at a certain stage of their existence, is helpful in treatment.
There is, I may remark, a very peculiar point regarding hæmaturic disease, the most deadly form of West Coast fever. This disease, so far as we know, has always been present on the South-West Coast, at Loando, the Lower Congo and Gaboon, but it is said not to have appeared in the Rivers until 1881, and then to have spread along the West Coast. My learned friend, Dr. Plehn, doubts this, and says people were less observant in those days, but the symptoms of this fever are so distinct, that I must think it also totally impossible for it not to have been differentiated from the usual remittent or intermittent by the old West Coasters if it had occurred there in former times with anything like the frequency it does now; but we will leave these theoretical and technical considerations and turn to the practical side of the question.
You will always find lots of people ready to give advice on
- ↑ See also Klebs and Tommasi Crudeli, Arch. f. exp. Path., xi.; Ceci, ibid, xv.; Tommasi Crudeli, La malaria de Rome, Paris, 1881; Nuovi studj sulla natura della Malaria, Rome, 1881; "Malaria and the Ancient Drainage of the Roman Hills," Practitioner, ii., 1881; Instituzioni de anat, Path., vol. i,, Turin, 1882; Marchiafava e Cuboni Nuovi studj sulla natura della Malaria, Acad. dei Lincei, Jan. 2; 1881; Marchand, Virch. Arch., vol. lxxxviii.; Laveran, Nature parasitaire des accidents d'intpaludisme, Paris, 1881; Richard, Comptes Rendus, 1881; Steinberg, Rep. Nal. Board of Health (U.S.), 1881. Malaria-krankheiten, K. Schwalbe; Berlin, 1890; Parkes, On the Issue of a Spirit Ration in the Ashantee Canpaign, Churchill, 1875; Zumsden, Cyclopædia of Medicine; Ague, Dr. M. D. O'Connell Calcutta 1885.
