- Chapter 1—Safety Appliances and Equipment on Railroad Engines and Cars, and Protection of Employees and Travelers (Repealed, see Chapters 203 to 209 and 213 of Title 49)
- Chapter 2—Liability for Injuries to Employees
- Chapter 3—Hours of Service of Employees (Repealed, see Chapters 211 and 213 of Title 49)
- Chapter 4—Care of Animals in Transit (Repealed, See Chapter 39 of Title 46 and Section 80502 of Title 49)
- Chapter 5—Government-Aided Railroads (Repealed or Transferred)
- Chapter 6—Mediation, Conciliation, and Arbitration in Controversies Between Carriers and Employees (Repealed)
- Chapter 7—Adjustment Boards and Labor Boards (Repealed)
- Chapter 8—Railway Labor
- Chapter 9—Retirement of Railroad Employees
- Chapter 10—Tax on Carriers and Employees (Repealed or Omitted)
- Chapter 11—Railroad Unemployment Insurance
- Chapter 12—Temporary Railroad Unemployment Insurance Program
- Chapter 13—Railroad Safety (Repealed, see Chapters 201 and 213 of Title 49)
- Chapter 14—Rail Passenger Service (Repealed, see Chapters 241 to 247 of Title 49)
- Chapter 15—Emergency Rail Services
- Chapter 16—Regional Rail Reorganization
- Chapter 17—Railroad Revitalization and Regulatory Reform
- Chapter 18—Milwaukee Railroad Restructuring
- Chapter 19—Rock Island Railroad Employee Assistance
- Chapter 20—Northeast Rail Service
- Chapter 21—Alaska Railroad Transfer
- Chapter 22—Conrail Privatization
