Phytochemical study for the pharmacological activity is an important segment of drug designing. This initial work establishes a foundation for product development. The pharmacological active compounds are finally developed into a pharmaceutical preparation. This is used in actual clinical and therapeutical practice to cure miscellaneous pathological problems. Thus; we have aimed this study for the extraction of compounds using two solvents of different polarities, so that maximum number of compounds can be extracted. Analytical technique used for the isolation and identification of the various compounds is thin layer chromatography. Phytochemical analysis of aerial parts showed the presence of Tannins, saponin and cardiac glycosides. Cardioactive glycosides, Tannin and saponin were reported in aerial parts of Ranunculus muricatus for the first time. Therefore Ranunculus muricatus can be used for further isolation and structural determination of cardioactive compounds.[1]