DEFIANCE, a city and the county seat of Defiance county, Ohio, U.S.A., at the confluence of the Auglaize and Tiffin rivers with the Maumee, about 50 m. S.W. of Toledo. Pop. (1890) 7694; (1900) 7579 (960 foreign-born); (1910) 7327. It is served by the Baltimore & Ohio and the Wabash railways, and by the Ohio Electric railway to Lima (42 m.). The city commands a fine view of the rivers and the surrounding country, which is well adapted to agriculture; and has large machine shops and several flour mills, besides manufactories of agricultural implements, waggons, sashes and blinds, and wood-working machinery for the manufacture of artillery wheels. Here, too, is Defiance College, an institution of the Christian Denomination, opened in 1885. Defiance was long the site of an Indian village. In 1794 General Anthony Wayne built a fort here and named it Defiance. In 1822 Defiance was laid out as a town; in 1845 it was made the county seat of the newly erected county; and in 1881 it became a city of the second class.