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GUAYMAS, or San José de Guaymas, a seaport of Mexico, in the state of Sonora, on a small bay opening into the Gulf of California a few miles W. of the mouth of the Yaqui river, in lat. 27° 58′ N., long. 110° 58′ W. Pop. (1900) 8648. The harbour is one of the best on the W. coast of Mexico, and the port is a principal outlet for the products of the large state of Sonora. The town stands on a small, arid plain, nearly shut in by mountains, and has a very hot, dry climate. It is connected with the railways of the United States by a branch of the Southern Pacific from Benson, Arizona, and is 230 m. S. by W. of the frontier town of Nogales, where that line enters Mexico. The exports include gold, silver, hides and pearls.