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misfortunes of his patron, and the ruin of the Sforza family, to quit Milan, Leonardo betook himself to Florence, and his inducements to this resolution seem to have been the residence there of the Medici family, the great patrons of arts, and the good taste of its principal inhabitants^[1], rather than its vicinity to the place of his birth; for which, under the circumstances that attended that event, it is not probable he could entertain much, if any predilection. The first work which he here undertook was a design for an altar-piece for the chapel of the college of the Annunciati. Its subject was, our Saviour, with his mother, St. Ann, and St. John; but though this drawing is said to have rendered Leonardo very popular among his countrymen, to so great a degree, that numbers of people went to see it, it does not appear that any picture was painted from it, nor that the undertaking ever proceeded farther than a sketch of a design, or rather, perhaps, a finished drawing. When Leonardo some years afterwards went into France^[2], Francis the First was desirous of having a picture from this drawing, and at his desire he then put it into colours; but whether even this last was a regular picture, or, which is more proba-

1. Du Fresne.
2. Vasari, 39. Du Fresne.