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A Human Experiment in Nerve Division
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compasses, applied simultaneously, could not be appreciated, but localization was preserved.

Forty-three days after the operation (June 7), the extent of the cutaneous analgesia had begun to diminish.


Fifty-six days after the operation (June 20), the analgesia on the forearm had greatly diminished, and the thumb had become sensitive to prick.


Eighty-six days after the operation (July 20), the whole forearm responded to prick, and the back of the hand was becoming rapidly sensitive to this form of stimulation. Cold was not appreciated except over the terminal phalanx of the thumb, and 50° C. gave rise to no sensation of heat.


One hundred and twelve days after the operation (August 15), the proximal part of the affected area over the forearm had become sensitive to cold.


One hundred and thirty-seven days after the operation (September 9), the whole forearm had become sensitive to cold.


One hundred and fifty-two days after the operation (September 24), the whole of the affected area, excepting a small spot on the back of the hand, had become sensitive to prick; the trophic sore healed.

One hundred and sixty-one days after the operation (October 3), cotton wool began to produce a diffuse tingling sensation over the forearm when the hairs were stimulated, but the whole of the affected area still remained insensitive to von Frey's tactile hairs. About the same time, the proximal patch on the forearm began to be sensitive to heat, and a definite heat-spot was discovered in this position.


One hundred and seventy-three days after the operation (October 15), the whole of the back of the hand had become sensitive to prick and, in a less degree, to cold.


One hundred and ninety days after the operation (November 1), the first heat-spot was discovered on the back of the hand.


Two hundred and twenty-five days after the operation (December 6), the hairs on the back of the hand responded with a diffused tingling to cotton wool, but the whole affected area of the forearm and hand still remained insensitive to von Frey's tactile hairs. This sensibility to cotton wool disappeared at once, if the arm was carefully shaved.


Three hundred and sixty-five days after the operation (April 24,1904), the proximal patch on the forearm began to be sensitive to cotton wool after shaving.

Between four hundred and seven and four hundred and twenty-eight