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LECTURE IV
Action of a nerve—Rapidity of nerve-current—Nature of nerve-current—Analogy with electric current—Nerveless animals—Heat in muscle—Muscles liberate mechanical energy and heat—Chemical changes in muscle.

We have now seen that the living matter forming a muscle is irritable or excitable, that is to say, it responds or reacts to a stimulus. We have also learned that the muscle shows its response or reaction by a contraction. Lastly, we have found that the natural stimulus that sets the muscle into action is something that happens in a nerve. Let us to-day, in the first place, study more carefully than we have yet done what occurs in a nerve.

A nerve, like a muscle, is composed of living matter, and this living matter, like all living matter, is irritable; but it does not show its irritability in any way evident to our senses. Suppose I irritate a little bit of nerve, which I have every reason to think is still alive,