METHYL CELLOSOLVE ACETATE
CH3COOCH2CH2OCH3
MW: 118.15
METHOD: 1451, Issue 2
CAS: 110-49-6
EVALUATION: FULL
OSHA : 25 ppm (skin) NIOSH: 0.1 ppm (skin) ACGIH: 5 ppm (skin) (1 ppm = 4.83 mg/m 3 @ NTP)
1451
PROPERTIES:
RTECS: KL5950000
Issue 1: 6 December 1974 Issue 2: 15 August 1994
liquid; BP 145 °C; MP -65 °C; Flash point 49 °C; d 1.005 @ 20 °C; VP 2 mm Hg (1700 mg/m 3) @ 20 °C
SYNONYMS: 2-methoxyethyl acetate; glycol monomethyl ether acetate; ethylene glycol monomethyl ether acetate
SAMPLING SAMPLER:
SOLID SORBENT TUBE (coconut shell charcoal, 100 mg/50 mg)
FLOW RATE:
0.01 to 0.2 L/min
VOL-MIN: -MAX:
0.2 L @ 25 ppm 20 L
SHIPMENT:
routine
MEASUREMENT TECHNIQUE:
GAS CHROMATOGRAPHY, FID
ANALYTE:
methyl cellosolve acetate
EXTRACTION:
carbon disulfide, 1 mL
INJECTION VOLUME:
5 µL
SAMPLE STABILITY:
at least 15 days @ 0 °C [1]
TEMPERATURE-INJECTOR: -DETECTOR: -COLUMN:
225 °C 250 °C 90 °C
BLANKS:
2 to 10 field blanks per set
CARRIER GAS:
helium, 30 mL/min
COLUMN:
10 ft x 1/8-in stainless steel packed with 5% FFAP stationary phase on 100/200 mesh Supelcoport
CALIBRATION:
standard solutions of methyl cellosolve acetate in carbon disulfide
RANGE:
30 to 4500 µg per sample [2]
ACCURACY RANGE STUDIED:
51 to 214 mg/m 3 [2] (20-L samples)
BIAS:
- 0.4%
ˆ ): OVERALL PRECISION (S rT
0.078 [2]
ACCURACY:
± 13.3%
ESTIMATED LOD: 10 µg per sample [2] PRECISION (Sr):
0.0441 [2]
APPLICABILITY: The working range is 0.3 to 47 ppm (1.5 to 225 mg/m 3) for a 20-L air sample. Better sensitivity may be achieved if a capillary column is used in place of a packed column. A 30-m x 0.32-mm fused silica capillary column coate d internally with 1.0 µm of DB-5, with appropriate instrument conditions, is recommended.
INTERFERENCES: High humidity conditions may cause inefficient collection of organic vapors.
OTHER METHODS: This is an adaptation of NIOSH Method S39 [2] and OSHA Method 53, issued 1/85. [1] Operational modifications [3] to the OSHA method are as follows: column -30 m x 0.32-mm I.D. fused silica capillary coated with 1.0 µm DB-5. Column temperature: 40 °C for 4 min and programmed at 4 °C/min. to 85 °C. Desorption: 30 min in 1.0 mL methylene chloride/methanol, 95/5(v/v) containing 1 µL/mL toluene as internal standard.
NIOSH Manual of Analytical Methods (NMAM), Fourth Edition, 8/15/94
