2-NITROPROPANE (CH3)2CHNO2
MW: 89.09
METHOD: 2528, Issue 2
2528
CAS: 79-46-9
RTECS: TZ550000
EVALUATION: FULL
OSHA : 25 ppm NIOSH: lowest feasible; suspect carcinogen; Group I Pesticide ACGIH: 10 ppm; suspect carcinogen (1 ppm = 3.64 mg/m 3 @ NTP)
PROPERTIES:
Issue 1: 15 August 1987 Issue 2: 15 August 1994
liquid; d 0.9821 g/mL @ 25 °C; BP 120 °C; MP -91 °C; VP 2.4 kPa (18 mm Hg; 2.4% v/v) @ 25 °C; lower explosive limit 2.6% (v/v) in air
SYNONYMS: dimethylnitromethane; sec-nitropropane.
SAMPLING
MEASUREMENT
SAMPLER:
SOLID SORBENT TUBE (Chromosorb 106, 100 mg/50 mg)
TECHNIQUE:
GAS CHROMATOGRAPHY, FLAME IONIZATION DETECTOR
FLOW RATE:
0.01 to 0.05 L/min
ANALYTE:
2-nitropropane
VOL-MIN: -MAX:
0.1 L @ 25 ppm 2 L [1]
DESORPTION:
1 mL ethyl acetate; stand 30 min
SHIPMENT:
routine
INJECTION VOLUME:
5 µL
100% recovered after 7 days @ 25 °C + 21 days @ 0 C [1]
TEMPERATURE-INJECTION: -DETECTOR: -COLUMN:
2 to 10 field blanks per set
CARRIER GAS:
He or N 2, 20 mL/min
COLUMN:
stainless steel, 6-m x 4-mm ID, packed with 10% FFAP on 80/100 mesh Chromosorb WHP
CALIBRATION:
standard solution of 2-nitropropane in ethyl acetate
RANGE:
10 to 150 µg per sample [1]
SAMPLE STABILITY:
BLANKS:
ACCURACY RANGE STUDIED:
BIAS:
3.1 to 28.3 mg/m 3 (3-L samples) [1]
190 C 200 C 90 C
2.8% [1]
ˆ ): 0.05 [1] OVERALL PRECISION (S rT ESTIMATED LOD: 1 µg per sample [1] ACCURACY:
± 11.4% PRECISION (Sr):
0.03 @ 0.01 to 0.1 mg per sample [1]
APPLICABILITY: The working range is 1.4 to 27 ppm (5 to 100 mg/m 3) for a 2-L air sample.
INTERFERENCES: The method has been evaluated in epoxy spray paint operations with no apparent interference from methyl butyl ketone, heptane, 1-nitropropane, toluene and xylene [2]. The Chromosorb 106 must be extracted with acetone [1]; ot herwise autosampler needles will be readily plugged.
OTHER METHODS: This revises P&CAM 272 [3].
NIOSH Manual of Analytical Methods (NMAM), Fourth Edition, 8/15/94
