HYDROQUINONE
HOC6H4OH
MW: 110.11
METHOD: 5004, Issue 2
CAS: 123-31-9 EVALUATION: FULL
OSHA : 2 mg/m 3 NIOSH: C 2 mg/m 3/15 min ACGIH: 2 mg/m 3
5004
RTECS: MX3500000 Issue 1: 15 February 1984 Issue 2: 15 August 1994
PROPERTIES: solid; MP 170 °C; BP 285 °C @ 730 mm; VP 0.0024 Pa (1.8 x 10 -5 mm Hg; 0.11 mg/m 3) @ 25 °C
SYNONYMS: 1,4-benzenediol; hydroquinol; quinol; 1,4-dihydroxybenzene.
SAMPLING SAMPLER:
FILTER (0.8-µm cellulose ester membrane)
FLOW RATE:
1 to 4 L/min
VOL-MIN: -MAX:
30 L @ 2 mg/m 3 180 L
FIELD TREATMENT:
transfer filter immediately to jar with 10 mL 1% acetic acid
SHIPMENT:
ship sample solutions
SAMPLE STABILITY:
at least 7 days @ 25 °C
BLANKS:
2 to 10 field blanks per set
MEASUREMENT TECHNIQUE:
HPLC, UV DETECTION
ANALYTE:
hydroquinone
EXTRACTION:
1% acetic acid, 10 mL
INJECTION VOLUME: 100 µL MOBILE PHASE:
1% acetic acid in H 2O; 1 mL/min
COLUMN:
25 cm x 4.6-mm ID Partisil 10-ODS, µ-Bondapack C 18 or equivalent; ambient temperature, 400 to 600 psi (2800-4100 kPa)
DETECTOR:
UV @ 290 nm
CALIBRATION:
solutions of hydroquinone in 1% aqueous acetic acid
RANGE:
0.06 to 0.8 mg per sample [2]
ESTIMATED LOD:
0.01 mg per sample [3]
PRECISION (Sr):
0.030 [1]
ACCURACY RANGE STUDIED:
0.8 to 4 mg/m 3 [1] (90-L samples)
BIAS:
4.4%
ˆ ): 0.061 OVERALL PRECISION (S rT ACCURACY:
± 15.0%
APPLICABILITY: The working range is 0.7 to 8 mg/m 3 for a 90-L air sample or 2 to 25 mg/m 3 for a 30-L air sample. This method can be used when significant concentrations of hydroquinone vapor are not present.
INTERFERENCES: None known. Hydroquinone is unstable on the collection media and must be stabilized immediately after collection by dissolution in 1% acetic acid.
OTHER METHODS: This is Method S57 [2] in a revised format. The method also appears in a NIOSH recommended standard [4].
NIOSH Manual of Analytical Methods (NMAM), Fourth Edition, 8/15/94
