p-NITROANILINE
H2NC6H4NO2
MW: 138.14
METHOD: 5033, Issue 1
CAS: 100-01-6
5033
RTECS: BY7000000
EVALUATION: FULL
OSHA : 6 mg/m 3 (skin) NIOSH: 3 mg/m 3 (skin) ACGIH: 3 mg/m 3 (skin)
PROPERTIES:
Issue 1: 15 August 1994
yellow crystals; MP 146 °C; BP 332 °C; VP 0.02 Pa (1.5 x 10 -4 mm Hg) @ 20 °C
SYNONYMS: 4-nitrobenzenamine, p-aminonitrobenzene, p-nitrophenylamine
SAMPLING SAMPLER:
FILTER (0.8 µm mixed cellulose ester membrane)
FLOW RATE:
1 to 3 L/min
VOL-MIN: -MAX:
16 L @ 6 mg/m 3 350 L
SHIPMENT:
routine
SAMPLE STABILITY:
at least 7 days @ 25 °C
BLANKS:
2 to 10 field blanks per set
MEASUREMENT TECHNIQUE:
HPLC, UV DETECTION
ANALYTE:
p-nitroaniline
EXTRACTION:
5 mL isopropanol
MOBILE PHASE:
40% isopropanol/60% hexane isocratic, 1 mL/min
COLUMN:
silica (Partisil 10, 25-cm x 4.6-mm x 6.4mm stainless steel)
DETECTOR:
UV @ 375 nm
CALIBRATION:
solutions of p-nitroaniline in isopropanol
RANGE:
100 to 2000 µg per sample [1]
ACCURACY ESTIMATED LOD: 20 µg per sample [1] RANGE STUDIED:
BIAS:
3.9 to 12.9 mg/m 3 (90-L samples) [1]
PRECISION (Sr):
0.020 [1]
-1.7%
ˆ ): 0.054 for range studied [1] OVERALL PRECISION (S rT ACCURACY:
±11.0%
APPLICABILITY: The working range is 1.1 to 22 mg/m 3 for a 90-L air sample. This method is applicable to p-nitroaniline aerosol but not for environments where vapor may be present.
INTERFERENCES: None identified.
OTHER METHODS: This revises Method S7 [2].
NIOSH Manual of Analytical Methods (NMAM), Fourth Edition, 8/15/94
