p-TOLUENESULFONIC ACID
C7H8O3S
MW: 172.20
METHOD: 5043, Issue 1
5043
CAS: 104-15-4
RTECS: XT6300000
EVALUATION: PARTIAL
OSHA : no PELs NIOSH: no RELs ACGIH: no TLVs (1 ppm = 7.03 mg/m3 @ NTP)
PROPERTIES:
Issue 1: 15 January 1998
solid; MP 106 to 107 C when anhydrous; d 1.20 g/mL @ 20 C; BP 140 C @ 20 mm Hg; VP not significant @ 25 C
NAMES & SYNONYMS: 4-methylbenzenesulfonic acid; p-methylphenylsulfonic acid; tosic acid
SAMPLING
MEASUREMENT
SAMPLER:
FILTER (13-mm glass fiber)
FLOW RATE:
1 to 3 L/min
VOL-MIN: -MAX:
10 L @ 1000 L
SHIPMENT:
routine
SAMPLE STABILITY:
at least 29 days @ 25 C [1]
BLANKS:
2 to 10 field blanks per set
EXTRACTION:
2 mL 2% isopropanol in water v/v; ultrasonic bath, 10 min
100 µL
COLUMN:
3.9-mm ID x 15 cm stainless steel packed with 10-µm µ-Bondapak C18
DETECTOR:
UV @ 222 nm
CALIBRATION:
standard solutions of ptoluenesulfonic acid in isopropanol: water
RANGE:
0.27 to 120 µg/sample [1]
not determined
ESTIMATED LOD:
0.08 µg/sample [1]
not determined
PRECISION ( r):
0.046 @ 3 to 15 µg/sample [1]
BIAS:
not determined
ACCURACY:
p-toluenesulfonic acid
21% acetonitrile/79% water containing 0.005 M Pic® A v/v; 1 mL/min
not studied
):
ANALYTE:
MOBILE PHASE:
RANGE STUDIED:
rT
HPLC, UV DETECTOR
INJECTION VOLUME:
ACCURACY
OVERALL PRECISION (
TECHNIQUE:
APPLICABILITY:p-Toluenesulfonic acid at 0.0027 to 1.2 mg/m3 can be determined in a 100-L air sample by this method. This method has been used to analyze samples collected at a foundry & machining company where p-toluenesulfonic acid was a catalyst in a process to produce a resin from resorcinol and furfuryl alcohol [2].
INTERFERENCES: None identified.
OTHER METHODS: Chromatographic methods for determination of p-toluenesulfonic acid in solution have been published [3-7]. None has been published for air analysis. An alternative air sampler for the present method is a midget impinger containing isopropanol [1,2].
NIOSH Manual of Analytical Methods (NMAM), Fourth Edition
