METHAMPHETAMINE . . .on Wipes by Liquid-Liquid Extraction: METHOD 9106, Issue 1, dated 17 October 2011 - Page 12 of 31
Table 3. Physical properties of analytes(1) Compound (alphabetically)
CAS
m.p.(°C)
Vapor Pressure (mm Hg)
pKa(4) 10.1 @ 20 °C
Log P(5)
Solubility in Water, g/100 mL 2.8 @ 25 °C
(DL)-Amphetamine
300-62-9
—
—
(D)-Amphetamine
51-64-9
<25
—
9.9
1.76
—
(D)-Amphetamine sulfate
51-63-8
>300
—
—
6.81
—
(L)-Amphetamine
156-34-3
—
0.201 @ 25 °C
10.1 @ 20 °C
1.76
2.8 @ 25 °C
Caffeine
58-08-2
238
15 @ 89 °C
10.4 @ 40 °C
-0.07
2.16 @ 25 °C
(DL)-Ephedrine
90-81-3
76.5
—
—
0.68
—
(L)-Ephedrine
299-42-3
34
0.00083 @ 25 °C
10.3 @ 0 °C
1.13
6.36 @ 30 °C
(L)-Ephedrine HCl
50-98-6
218
2.04E-10 @ 25 °C
pH 5.9 @ 1/200 dil.(3)
-2.45
25(6)
MDEA
82801-81-8
—
—
—
—
—
MDMA HCl
42542-10-9
148-149(2)
—
—
—
—
(D)-Methamphetamine
537-46-2
—
0.163 @ 25 °C
9.87 @ 25 °C
2.07
1.33 @ 25 °C
(D)-Methamphetamine HCl
51-57-0
170-175(2)
—
—
—
—
Phencyclidine
77-10-1
46.5
—
8.29
4.69
—
Phencyclidine HCl
956-90-1
233-235(2)
—
—
—
—
Phentermine
122-09-8
—
0.0961 @ 25 °C
—
1.90
1.86 @ 25 °C
Phentermine HCl
1197-21-3
198(2)
—
—
—
—
(±) Phenylpropanolamine
14838-15-4
—
0.000867 @ 25 °C
9.44 @ 20 °C
0.67
14.9 @ 25 °C
(±) Phenylpropanolamine HCl
154-41-6
194
—
—
-2.75
—
(L)-Norephedrine
492-41-1
51-53
—
—
—
—
1S,2S (+)-Norephedrine
36393-56-3
77.5-78
0.000867 @ 25 °C
0.83
14.9 @ 25
1S,2S (+)-Norephedrine HCl
492-39-7
—
—
0.22
2 @ 25
(D)-Pseudoephedrine
90-82-4
119
0.00083 @ 25 °C
9.44 @ 20 pH 5.9-6.1 in aq. soln. (3) 10.3 @ 0 °C
0.89
10.6 @ 25 °C
(D)-Pseudoephedrine HCl
345-78-8
181-182(2)
—
pH 5.9 @ 1/200 dil.(3)
—
—
(1) (2) (3) (4) (5) (6)
(3)
1.76
Handbook of Physical Properties of Organic Chemicals unless otherwise noted [17]. Merck Index [10]. Sigma-Aldrich MSDS [14]. Negative log of the acid dissociation constant for the amine in aqueous solution. Log P = octanol-water partition coefficient. Temperature not given in source.
Method rev. 1.1.1
NIOSH Manual of Analytical Methods (NMAM), Fifth Edition
