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ther, as may be seen in Shambles: Whereas, if there were such a thing as a Parenchyma, that certainly would, like a hungry Sponge, immediately swell up in several parts, (which without much difficulty might be discover'd in dissection) and more eminently, where it should find the pores most patent: And in the dissection of such Muscles it would be very strange, not to find some, if not many, pieces of them in various shapes, to the great inconvenience of the parts, in which they are seated: Which yet I confess I could never find in any Muscle, unless it were where there had been a Contustion, or an Inpostume, or the like. But according to my opinion of the Parenchymous parts, the reason, why the Flesh of a very lean Oxe or Cow, that hath got new Flesh in a good pasture, eats tenderer, seems to be this: That in a very lean Best the Vessels desseined for admitting and distributing the nourishing Juice, are so near contracted, and lye so close together, that, when once they are relax'd, by the fresh and unctuous nourishment, they extend every way in all extensive parts, until in a short time the whole Creature is, as it were, created a new, having got new flesh upon old bones: And the necessity of extreme extension makes all those parts, that are, as has been said, for the admission of nourishment, so thin and fine, that it will make the lean Beast, put into a rich pasture, eat young and tender: Whereas one of the same Age, that never was very poor, fed in the same pasture, shall eat hard and tough.

3.it has been observed, that Corpulent Persons in some Diseases, that seize on them, do fall away to wonder, not only in the Wast, but in the Arms, Legs, and Thighs; and the very Calves of the Legs have been observed so flaccid and loose, that one might wrap the skin about the bones. The reason whereof, according to the opinion deliver'd, may be easily rendred to be, A great Consumption of the Stock of Liquors, that in Health kept the Vessels turgid; Which Vessels I suppose to make up those Muscles. But when the Pores are obstructed, that the nourishment is hindred (which then also uses to be but sparingly administred) and sweats, either spontaneous, or forced, are large, there must needs be a great expence of those Liquors, the supply being but inconsiderable: which cannot but contract all these ducts of all sorts nearer together, and make them much less in themselves, meerly from Exhaustion: Or, if there should be no sweats, the internal Heat spends the spirits, and dries up the Liquors; the consequence whereof may reasonably be presumed to be this Flaccidity of parts, and great and sudden Change, made in them; not that there is need of any Parenchyma to fill up these Muscles, considering what hath been said. Mean while, I humbly conceive, that if it be in any part of a Muscle, their Ingenuity, that plead for it, will put them upon some experiments, to bring it to Ocular Demonstration, either in a Living or Dead Muscle, any kind of flesh, raw, rosted, boyl'd, or in what they can best make it out. And when I shall be convinc'd of an Errour in what I have discoursed, I shall beg pardon for giving the Occasion of the trouble of that Experiment, which shall prove a

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Parenchyma