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great reluctance, another dose early in the morning. In less than three hours he was again taken very ill, with anxiety, a sense of trembling over the whole body, and as if prickling sparks were flying out every where.—When I came to him, he begged me to change this medicine, and said it was like to have killed him. Having heard all his complaints, I made the pills be put away, and promised he should have no more of them: but his fear and aversion were so great, that the moment I was gone he ordered the box to be taken out of the house and thrown quite away.

10th, He passed this night tolerably, and found himself much better in the morning: but the complaints came by turns as before.

From this till the 20th, I gave him sundry medicines, but with little more effect than to ease him now and then: for the complaints always returned again in different manners and at uncertain times: but nothing extraordinary happened.

On the 20th, I gave him a dose of Epsom salt, which he had been used to take: it purged very well; but, immediately on its leaving off to work, his body struck out with great numbers of small red spots, without other inconvenience except a little extraordinary heat in the skin.

21st, The spots were almost gone, and he found himfelf more cool and easy than before.

22d, He took another dose, and the spots returned in the same way more than the first day: he found also the same relief. After this he took more doses of the same salt, always intermitting a day or two. The spots returned, but every time fewer appeared; and at last none appeared on taking these salts.

The