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THE POPULAR SCIENCE MONTHLY.

In the last two decades of the last century, scientific effort concerned itself chiefly with accumulating knowledge concerning fungi and insects. Vast numbers of these were classified, catalogued and described. In other words, the means of diagnosis were perfected and diseases were grouped into natural classes according to their causal agents. Attempts toward the development of methods of treatment by the use of various sprays were more or less effective. Indeed, spraying had been advocated to some slight extent for a century or more as a remedy for insect and other plant diseases. The variety of spraying substances recommended ranged from clay, ashes and cow manure to sulphur, lime, salt, etc. One writer recommended "The applying around the base of the tree; flax, rubbish, sea weed, ashes, lime, sea shells, sea sand, mortar, clay, tanner's bark, leather scraps, etc."—evidently not a homeopathic prescription. The variety of substances recommended raises suspicion that the efficiency of no formula was demonstrated. In 1787 we find the heroic advice, 'just wet the trees infested with lice, then rub flowers of sulphur upon the insects, and it will cause them all to burst.' Some decided progress was, however, made. As early as 1842, a whale soap was used and retained favor; quassi, hellebore and tobacco were standard insecticides as early as 1855. Sulphur was used for the mildews and bluestone for wheat smut.

The last twenty years of the nineteenth century mark the beginning of a new epoch in plant protection. For this there are three reasons: first the increased aggressiveness of a certain fungous disease, the grape mildew, in Europe; second, the rapid spread of the potato bug, somewhat pedantically termed the Colorado beetle, and, third, resulting from these two, revolutionary changes in materials and methods for treating plant diseases, both fungous and insect, in the new world and in the old. It is a matter not entirely without interest that the revolution in European methods may be definitely traced to typical American aggressiveness, inasmuch as the activity arousing fungus was of American importation.

In Europe the invasion of the downy mildew of the grape in 1878 was unchecked by the most vigorous fungicides then used. All are familiar with the story of the great benefit conferred upon humanity through the predatory habits of the French boys in the vineyards that produce the famous Bordeaux wines. The rows lying nearest the roadway were sprinkled with verdigris or a mixture of lime and bluestone, to give the impression that the fruit was poisoned. In 1882 Millardet, of the faculty of the sciences, noticed that the vines thus treated held their leaves while others succumbed to the mildew. He ascribed this effect to its proper cause, and conducted carefully systematized experiments, which resulted in giving to the world bouillie