rature of animals is soon raised to 11° or even 16° above what it had been previously, and death speedily ensues. The rapid diminution or even total suppression of the cutaneous exhalation, on the other hand, is by no means followed by a rise in the temperature of the body. In general dropsies, which are attended with a remarkable diminution of this secretion, an icy coldness usually pervades both the body and the limbs. A great fall in the animal temperature was found by Fourcauld, Becquerel and Breschet to be the effect of covering the body with a varnish impervious to perspiration ; and so serious was the general disturbance of the functions in these cir- cumstances, that death usually ensued in the course of three or four hours.
The question will next arise, how does it happen that health and even life can be so immediately dependent as we find them to be on the elimination of so small a quantity of water as thirty-three ounces from the general surface of the body in the course of twenty-four hours? To this the author answers, that such elimination is important as securing the conditions which are necessary for the endosmotic trans- ference between arteries and veins of the fluids which minister to nutrition and vital endowment. It is admitted by physiologists that the blood, while still contained within its conducting channels, is inert with reference to the body, no particle of which it can either nourish or vivify until that portion of it which has been denomina- ted the plasma has transuded from the vessels and arrived in imme- diate contact with the particle that is to be nourished and vivified : but no physiologist has yet pointed out the efficient cause of these tendencies of the plasma, first, to transude through the wall of its efferent vessels, and secondly, to find its w^ay back again into the afferent conduits. The explanation given by the author is that, in consequence of the out-going current of blood circulating over the entire superficies of the body perpetually losing a quantity of water by the action of the sudoriparous glands, the blood in the returning channels has thereby become more dense and inspissated, and is brought into the condition for absorbing, by endosmosis, the fluid perpetually exuding from the arteries, which are constantly kept on the stretch by the injecting force of the heart.
In an appendix to the paper, the author points out a few of the practical applications of which the above-mentioned theory is suscep- tible. Interference wdth the function of the skin, and principally through the agency of cold, he observes, is the admitted cause of the greater number of acute diseases to which mankind, in the tempe- rate regions of the globe, are subject. He who is said to have suf- fered a chill, has, in fact, suff'ered a derangement or suppression of the secreting action of his skin, a process which is altogether indis- pensable to the continuance of life ; and a disturbance of the general health follows as a necessary consequence. Animals exposed to the continued action of a hot dry atmosphere die from exhaustion ; but when subjected to the eff'ects of a moist atmosphere of a temperature not higher than their own, they perish much more speedily ; being
