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After he had made out the actions of the heart he fell at once upon the problem of the total amount of blood, and tried to determine this in animals, such as sheep and dogs. He then made out the capacity of the ventricles. In man he found the left ventricle would hold two ounces of blood; now his difficulty was to know how much it propelled into the aorta at each contraction, and I imagine that he did not succeed in doing this to his satisfaction, as he gives no experiments on the point. But he says, “Let us suppose, as approaching the truth, that a fourth, fifth, or sixth, or even but the eighth part of its charge is thrown into the artery.” Then, counting the pulse, he shows that in half an hour far more blood must pass through the heart than all the blood in the body. In the case of the sheep he says that if only one scruple passes at each contraction, in one half hour ¾ lb. would pass, but the sheep’s total blood is only 4 lb. But it is obvious he had a still clearer idea of the great