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| Name | Entry in The World Factbook | |
| Sahel | Burkina; Cape Verde; Chad; The Gambia; Guinea-Bissau; Mali; Mauritania; Niger; Senegal | |
| Saigon (Ho Chi Minh City) | Vietnam | |
| St. Brandon | Mauritius | |
| St. Christopher and Nevis | St. Kitts and Nevis | |
| St. George's [US Embassy] | Grenada | |
| St. George's Channel | Atlantic Ocean | |
| St. John's [US Embassy] | Antigua and Barbuda | |
| St. Lawrence, Gulf of | Atlantic Ocean | |
| St. Lawrence Island | United States | |
| St. Lawrence Seaway | Atlantic Ocean | |
| St. Martin | Guadeloupe | |
| St. Martin (Sint Maarten) | Netherlands Antilles | |
| St. Paul Island | Canada | |
| St. Paul Island | United States | |
| St. Paul Island (Île Saint-Paul) | French Southern and Antarctic Lands | |
| St. Peter and St. Paul Rocks (Penedos de São Pedro e São Paulo) | Brazil | |
| St. Vincent Passage | Atlantic Ocean | |
| Saipan | Northern Mariana Islands | |
| Sakhalin Island (Ostrov Sakhalin) | Soviet Union | |
| Sala y Gómez, Isla | Chile | |
| Salisbury (Harare) | Zimbabwe | |
| Salvador de Bahia [US Consular Agency] | Brazil | |
| Salzburg [US Consulate General] | Austria | |
| Sanaa [US Embassy] | Yemen Arab Republic | |
| San Ambrosio | Chile | |
| San Andrés y Providencia, Archipiélago | Colombia | |
| San Bernardino Strait | Pacific Ocean | |
| San Félix, Isla | Chile | |
| San Jose [US Embassy] | Costa Rica | |
| San Luis Potosi [US Consular Agency] | Mexico | |
| San Miguel Allende [US Consular Agency] | Mexico | |
| San Salvador [US Embassy] | El Salvador | |
| Santa Cruz [US Consular Agency] | Bolivia | |
| Santa Cruz Islands | Solomon Islands | |
| Santiago [US Embassy] | Chile | |
| Santo Domingo [US Embassy] | Dominican Republic | |
| Sao Luis [US Consular Agency] | Brazil | |
| Sao Paulo [US Consulate General] | Brazil | |
| São Pedro e São Paulo, Penedos de | Brazil | |
| Sapporo [US Consulate General] | Japan | |
| Sapudi Strait | Indian Ocean | |
| Sarawak | Malaysia | |
| Sardinia | Italy | |
| Sargasso Sea | Atlantic Ocean | |
| Sark | Guernsey | |
| Scotia Sea | Atlantic Ocean | |
| Scotland | United Kingdom | |
| Scott Island | Antarctica | |
| Senyavin Islands | Micronesia, Federated States of | |
| Seoul [US Embassy] | Korea, South | |
| Serrana Bank | Colombia | |
| Serranilla Bank | Colombia | |
| Severnaya Zemlya (Northland) | Soviet Union | |
| Seville [US Consular Agency] | Spain | |
| Shag Island | Heard Island and McDonald Islands | |
| Shag Rocks | Falkland Islands (Islas Malvinas) | |
| Shanghai [US Consulate General] | China | |
| Shenyang [US Consulate General] | China | |
| Shetland Islands | United Kingdom | |
| Shikoku | Japan | |
| Shikotan (Shikotan-tō) | Japan |
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