Page:Thruston speech upon the progress of medicine 1869.djvu/15

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Antiseptic substances, able to prevent both fermentation and putrefaction, have also greatly increased in number and in use in medicine. Chief amongst them are carbolic and sulphurous acids, and the hypermanganate of potash. As means of destroying infection, used according to Dr William Budd's direction, they are likely to prove of invaluable service. As external agents, also, in surgical cases, they have already been very useful, especially in the hands of Prof. Lister of Glasgow[1]. They illustrate the value of perfect rest in the cure of disease, preserving the surfaces with which they are brought in contact from the intrusion of zymotic germs, and also preventing the acrid alterations of the animal-juices, which would otherwise interfere with natural curative efforts. Their action will probably throw some light upon the true value of other applications, which have been in use for many ages, such as lunar caustic, zinc, lead, copper, &c.

We cannot speak so decidedly of the beneficial action of these antiseptics administered internally in the form of sulphites, carbolates, sulpho-carbolates, &c. Since the interesting observations of Dr Polli with putrescent injections, different attempts have been made to cut short the morbid fermentation of diseases by these drugs, but hitherto the progress of zymotic diseases has not been materially affected by their use. They may however still prove useful in some cases.

But chemistry is beginning gradually to enter still further upon the interpretation of the action of remedies.

Dr Snow was the first to propound a theory of the chemical action of anæsthetics, and Dr Bence Jones has greatly extended his observations, claiming to account for

  1. See Address on the Antiseptic System of Treatment in Surgery, Brit. Med. Journal, July 18, 1868.