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known to pass into an obscure general fever, which has ended fatally; and that this mode of termination coincides with the effects ascribed to arsenic as the chief ingredient in the celebrated Aqua Toffana. But the latter phenomena, at best of doubtful authenticity, are not represented to have been preceded by the ordinary symptoms of violent irritation, or to have been developed except under the use of continuous small doses; and as for the more recent and less ambiguous cases of fever succeeding the usual primary effects of a large dose, in no instance yet recorded was there an intermission between the two stages. So much, then, for the force of the evidence drawn from the characters of the symptoms of general poisoning. According to the example of others, I might consider in the present place the force of evidence derived from the symptoms themselves, which distinguish the three classes of poisons. But this subject, together with the special natural diseases which imitate the symptoms of poisoning, will be treated of more conveniently as an introduction to each of the classes. Section II.Of the Evidence from Morbid Appearances.

The appearances left in the dead body after death by poison used formerly to be relied on as strongly as the symptoms during life; and with even less reason. Except in the instance of a very few poisons, the morbid appearances alone can never distinguish death by poison from the effects of natural disease, or from some other kinds of violent death. There is not much room, therefore, for general remarks under the present head.

It was at one time thought by the profession, and is still very generally imagined by the vulgar, that unusual blackness or lividity of the skin, indicates death by poison generally. But every experienced physician is now well aware, that excessive lividity is by no means universally produced by poison, and that it is likewise produced by so many natural diseases as not even to form, in any circumstances whatever, the slightest ground of suspicion. Neither is there any difference in kind, as some imagine, between the lividity which succeeds death by poison, and that which follows natural death. Yet it is right for the medical jurist to be aware that lividity as a supposed consequence of poison ought to be strictly attended to by medical inspectors and law officers while investigating charges of poisoning, because the vulgar belief on the subject sometimes leads to such conduct or language on the part of the poisoner as betrays his secret at the time, and constitutes evidence of his guilt afterwards.

Another appearance equally unimportant is early putrefaction of the body. Early putrefaction, at one time much insisted on as a criterion of poisoning,[1] cannot even justify suspicion. It is by no means invariably, or even generally caused by poisons; nay, some-*

  1. Alberti, Systema Jurispr. Medic, i. c. 13. § 4.