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subjects were children from seven to nine years of age; and they took, some of them one seed, and none more than five. Three scarcely suffered at all. One vomited the poison and got well at once. Of the others, some had only nausea and feebleness of the pulse, another had also dilatation of the pupils, some had vomiting and purging, others great drowsiness, others again both sets of symptoms. In all the pulse was weak and generally rapid. Emetics, laxatives and ammonia were administered with success.[1]

The leaves of this plant are stated by Vicat, a good authority, to possess the property of acting violently as an emetic and purgative;[2] and Cadet says the unripe pods have been known to produce in small quantities severe vomiting, and profuse, protracted diarrhœa.[3]

My attention was lately turned by a criminal trial in this country to the effects of the bark, which is not alluded to as a poison by any author, although its properties seem well known to the peasantry in the north of Scotland. A lad Gordon was tried lately at Inverness for administering poison to a fellow-servant, and it was proved that he gave her laburnum-bark in broth. She immediately became very sick, and was soon attacked with incessant vomiting and purging, pain in the belly, rigor, and extreme feebleness; and several days elapsed before she could return to her work. The sickness, vomiting, purging and pain continued afterwards to recur more or less; great emaciation ensued; in six weeks she was so much reduced as to be compelled to quit service; and even six months afterwards, she continued so ill with a chronic dysenteric affection, that fears were entertained for her life, although eventually she did recover. Being consulted in the case, I was inclined to rely in the general properties of the plant and the peculiar, intense, nauseous bitterness of the bark, even more intense there than in the seeds, as adequate proof that the bark was capable of producing the effects observed in this case. I was scarcely prepared, however, to find it so deadly a narcotic poison, as it proved to be on careful experiment. Dr. Ross of Dornoch, who saw the woman and was also consulted on the part of the crown in the case, found that from twenty to seventy grains of dried laburnum-bark caused speedy and violent vomiting when administered to dogs, but no other marked effect. I found that when an infusion of a drachm of dried bark was injected into the stomach of a strong rabbit, the animal in two minutes began to look quickly from side to side, as if alarmed and uncertain in which direction to go, then twitched back its head two or three times, and instantly fell on its side in violent tetanic convulsions, with alternating opisthotonos and emprosthotonos so energetic that its body bounded with great force upon the side up and down the room. Suddenly in half a minute more all motion ceased, respiration was at an end, and, excepting that the heart continued for a little to contract with some force, life was extinct. No morbid appearance was visible anywhere. The heart was gorged, but irritable. Dr. Ross subsequently repeated this experiment, and obtained analo-*

  1. Lancet, 1840-41, 552.
  2. Hist. des Plantes Ven. de la Suisse, 1776, p. 49.
  3. Bulletins de la Société de Pharmacie, 1809, p. 48.