Distribution, traditional uses, isolated chemical constituents and pharmacological activities of some common species of the genus Araucaria are reviewed in this paper. Almost 19 species belong to the genus, Araucaria. It is indigenous to North America. Biflavanoid, diterpene, phenyl propanoid and lignans are abundant in the genus. The most common pharmacological activity of Araucaria in modern medicines is anti-inflammatory. It also possesses other pharmacological activities such as antiulcer, antiviral, neuro-protective, anti-depressant and anti-coagulant. The aim of the present paper is to present an extensive review of the plants in this genus including their traditional uses, chemical constituents and pharmacology.[1]